My name is Prof. Hilary Edeoga, Editor, Journal of Medicinal Plants Research.
We received a manuscript titled: Investigations of the Methanolic Root Extract of Cochlospermum planchonii (Kunth) for Pharmacological Activities in vitro and in vivo
We will be most grateful if you could find time to review the manuscript. Please find the Abstract below:
Some pharmacological activities of Cochlospermum planchonii Kunth (Cochlospermaceae) root extract were investigated. The extract yielded 3.4 % w/w dry matter. The extract was well tolerated in all doses (250 – 3,000 mg/kg, p.o.) used in the experiment. Brine shrimps lethality test gave LC50 of 4.42 ppm at 95 % confidence interval. The extract significantly (p<0.05) increased pentobarbitone-induced sleeping time in all doses used. The extract (250, 500, and 1,000 mg/kg, p.o.) significantly (p<0.05) decreased the paw licking time in the second (late) phase of formalin analgesia test. Also, it significantly (p<0.05) decreased the number of acetic acid-induced writhing in all doses used. The anti-inflammatory study showed that the extract caused a biphasic inhibition of carrageenan-induced paw oedema, which was similar to indomethacin (20 mg/kg). Despite, the promising analgesic effect of the extract, it did not protect mice from leptazole-induced convulsions. It showed no antibacterial activity. The extract (250, 500, 1000 mg/kg, p.o.) significantly (p<0.05) decreased blood glucose levels in alloxan-induced hyperglycemic mice in a dose- and time-dependent manner. The phytochemical spot tests showed the presence of saponins, tannins, glycosides and carbohydrates. In conclusion, C. planchonii root extract contains very potent bioactive compounds, which showed CNS depressant, analgesic, anti-inflammatory, and antihyperglycaemic effects.
KEYWORDS: C. planchonii, analgesic, anti-inflammatory, bioactive, antihyperglycaemic.
Kindly send me an email to acknowledge the receipt of this mail so I could send you the full manuscript and I will be most grateful to hear from you.
Prof. Hilary Edeoga
Editor, Journal of Medicinal Plants Research
До сих пор думаю, что бы это значило. Ни к медицине, ни к лекарственным растениям я не имею ни малейшего отношения. А чо, может отрецензировать?